
Explore the benefits of a polynucleotide treatment at Skin Medical for a healthy skin boost.
Polynucleotides treatments are great for improving the quality of your skin and giving an instant, refreshed look. As we age, the body’s production of collagen declines, leading to the formation of wrinkles, fine lines, and sagging skin. By stimulating fibroblasts within the skin and enhancing collagen production, polynucleotides help restore firmness to the skin, resulting in a more youthful appearance. If you are looking for a more long-term approach to collagen restoration, you should be considering a collagen stimulator such as Lanluma, Ellanse or Sculptra which work in the deeper layers of the skin.
By stimulating your body’s natural regenerative processes, this treatment builds collagen, improves elasticity, and deeply hydrates, giving you gradual but long-lasting results.

At Skin Medical, we pride ourselves on delivering natural-looking results that enhance your beauty rather than altering it. Dr Sabika Karim and Dr Saif are trusted experts in aesthetic medicine, known for their patient-first approach and bespoke treatment plans.
From the initial consultation to post-treatment care, we’re here to ensure your journey is smooth, safe, and successful. If you’re ready to transform your skin, book your consultation today and let us help you achieve the glowing, youthful complexion you deserve.

As well as for facial rejuvenation, polynucleotides are effective for hair restoration, body contouring, and scar treatments.
In hair restoration, polynucleotides promote the growth and breadth of dermal papilla cells and improve blood circulation to the scalp, resulting in thicker, healthier hair. For body contouring, polynucleotides help to remodel tissues, leading to smoother, more sculpted contours.
In scar treatments, polynucleotides regulate fibroblast activity and collagen synthesis, helping to soften and refine the appearance of scars.

Polynucleotides are long chains of nucleotides, the building blocks of DNA and RNA. These chains possess unique properties that interact with cellular receptors, modulating essential signalling pathways and offering benefits in skin rejuvenation and other aesthetic applications.
Polynucleotides can be derived from various sources, including salmon DNA, or synthesised in a laboratory. Regardless of their origin, they retain the structural and functional properties necessary for their therapeutic effects.
Polynucleotide injections have shown efficacy in promoting collagen synthesis, tissue repair, and overall skin health. Results may vary among individuals, but many patients experience noticeable improvements in skin quality and appearance over time with consistent treatment.
The cost of polynucleotide therapy can vary depending on factors such as treatment area, the extent of the procedure, and geographic location. Our Polynucleotide treatments start from £300.
Individuals with fish allergies should exercise caution when considering polynucleotide therapy, particularly if derived from salmon DNA. Alternative sources or synthesised polynucleotides may be preferable for those with known allergies.
There is no specific age requirement for polynucleotide therapy, as suitability depends on individual skin concerns and treatment goals. Consultation with a qualified practitioner can help determine the most appropriate timing for treatment.
Polynucleotide therapy yields gradual results, with timelines varying based on individual response and the treated area. While some patients may notice improvements within a few weeks, optimal outcomes typically develop over time with consistent treatment.
Polynucleotide therapy is offered by qualified healthcare providers, including dermatologists, plastic surgeons, and aesthetic practitioners. Patients should seek treatment from reputable professionals experienced in administering injectable therapies.
Polynucleotide treatment is not usually painful, with minimal discomfort reported by most patients. Topical anaesthetics or numbing agents may be applied to enhance comfort during the procedure.
Following polynucleotide treatment at Skin Medical, most patients experience minimal downtime and can return to their normal routine almost immediately. Some mild redness, swelling and small bumps at the injection sites is entirely normal and typically settles within 24 to 48 hours. Results develop gradually as the treatment works at a cellular level to stimulate fibroblast activity, build collagen and deeply hydrate the skin, with visible improvements in tone, texture and radiance becoming apparent over the following weeks. A course of treatments is recommended for optimal results.
Polynucleotides are naturally derived, purified DNA fragments that actively stimulate the skin’s own regenerative processes from within. By encouraging collagen and elastin production and improving skin hydration, they deliver gradual, natural-looking improvements in skin quality without masking the signs of ageing. At Skin Medical, polynucleotide treatments are used for facial rejuvenation, hair restoration, body contouring and scar treatment, with every treatment plan personalised to your skin concerns and goals by Dr Sabika Karim and Dr Saif Abbas Chatoo.
To prepare for your polynucleotide appointment at Skin Medical:
During your appointment:
Polynucleotide treatment is a well-tolerated procedure with minimal downtime for most patients.
You may experience:
These effects are entirely normal and are a sign that the treatment has been administered correctly. Because polynucleotides work gradually by stimulating your skin’s own repair processes, there is no sudden or dramatic change immediately after treatment.
To support your skin’s recovery and help the treatment work as effectively as possible, we recommend the following after your appointment.
If you experience significant or worsening swelling, any signs of infection or unusual discomfort beyond 48 hours, please contact our team promptly.
Polynucleotides work by stimulating the skin’s own regenerative processes, which means improvements develop gradually and authentically over time.
Because polynucleotides regenerate rather than fill, the outcome is a gradual and authentic improvement that looks entirely natural and continues to build with each session.
Polynucleotide treatment may not be suitable if you have:
A full consultation will be carried out before treatment to confirm suitability and ensure the approach is personalised to your skin concerns and long-term goals.
Polynucleotide treatment is a safe and well-established regenerative procedure when performed by an experienced medical team. However, please contact Skin Medical if you experience:
We are here to support you following your treatment and to answer any questions as your skin continues to renew and regenerate.